[Scanning electronic microscope (SCM) examination of the hydroxylapatite (HA) combined with bone morphogenetic...

HA combined with BMP was implanted on the surface of rabbit's parietal bone and examined with SCM. The results indicate that there are a large amount of new bone formation within the combined material and the amount is increasing as the time lapsed. The new bone is directly connected with the HA particles, forming a bony interface between the host bone and the implants to integrate them. In contrast, there are a lot of fibrous tissues with a little new bone formed on the interface if HA is implanted alone. The result implies that the BMP plays a very important role in new bone formation and the combined material is ideal for alveolar ridge augmentation.