[Autologous pericardial patch angioplasty of Budd-Chiari syndrome]

Area of Science:

• Vascular Surgery
• Interventional Cardiology
• Regenerative Medicine

Context:

• Inferior vena cava (IVC) and hepatic vein (HV) stenosis can lead to severe complications like ascites, edema, and hepatic dysfunction.
• Traditional treatments may have limitations, necessitating innovative surgical approaches.

Purpose:

• To evaluate the efficacy and safety of autologous pericardial patch angioplasty for treating IVC or HV stenosis.
• To assess the long-term outcomes and patency rates of this reconstructive technique.

Summary:

• Twenty-one patients with IVC or HV stenosis underwent autologous pericardial patch angioplasty.
• All patients experienced uneventful recovery, with significant symptom improvement (ascites, edema, varices, hepatomegaly) within 1-3 months.
• Postoperative B-mode ultrasonography confirmed good patency of the reconstructed vessels in 18 patients, with 6 patients showing normalized hepatic function.

Impact:

• Autologous pericardial patch angioplasty offers a promising therapeutic option for IVC and HV stenosis.
• This technique demonstrates excellent short- and mid-term outcomes, improving patient quality of life and liver function.
• The study highlights the potential of using autologous tissue for vascular reconstruction in complex venous pathologies.