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Related Experiment Videos

The swine-influenza decision

S C Schoenbaum, B J McNeil, J Kavet

    The New England Journal of Medicine
    |September 30, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Mass immunization against swine-like influenza in 1976-1977 showed economic benefits varied by target population and acceptance rates. Limiting vaccination to adults over 25 could be justifiable if acceptance exceeds 59%.

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    Area of Science:

    • Public Health
    • Epidemiology
    • Health Economics

    Background:

    • The 1976-1977 swine-like influenza immunization program involved significant economic considerations.
    • Estimating epidemic likelihood and impact is crucial for public health interventions.

    Purpose of the Study:

    • To analyze the economic aspects of mass immunization against swine-like influenza.
    • To determine the cost-effectiveness of different vaccination strategies.

    Main Methods:

    • Delphi technique used to estimate epidemic probability and characteristics.
    • Economic modeling to assess costs and benefits of vaccination programs.

    Main Results:

    • Without intervention, an epidemic could cost over $6 billion (total population) and $3 billion (high-risk group).

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  • Net benefits depend on target population, administration costs, and vaccine acceptance.
  • With a 0.10 epidemic probability and $0.50/person cost, vaccinating the entire population is not optimal.
  • Restricting vaccination to adults 25+ is economically justifiable if acceptance exceeds 59%.

    • Conclusions:

    • Economic analysis does not necessitate limiting vaccination solely to high-risk groups.
    • Targeted vaccination strategies, like focusing on adults 25 and older with high acceptance, can be economically sound.
    • Cost-benefit analysis is essential for optimizing public health immunization programs.