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Effects of peritoneal fluids from patients with endometriosis on capacitated spermatozoa
P Bielfeld1, M A Graf, R S Jeyendran
1Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois.
Objective:
To determine the effects of peritoneal fluid (PF) from patients with endometriosis on capacitated sperm.
Design:
Capacitated donor sperm were allowed to migrate into straws filled with pooled PF from patients with unexplained infertility without endometriosis (n = 4) and those with mild (n = 4) and moderate-severe (n = 4) endometriosis, respectively, for 3 hours.
Main Outcome Measures:
Sperm motility, sperm membrane integrity, and acrosomal loss were determined.
Results:
Statistically, no significant differences were found among the various sperm parameters determined.
Conclusion:
Peritoneal fluid from patients with endometriosis does not appear to adversely affect capacitated spermatozoa.