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Conjunctival changes after subconjunctival lignocaine

B N Noureddin1, M Jeffrey, W A Franks

  • 1Eye Department, American University of Beirut, Lebanon.

Eye (London, England)
|January 1, 1993
PubMed
Summary
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Local anesthesia with lignocaine for open-angle glaucoma surgery resulted in more avascular blebs and lower post-operative intraocular pressure (IOP) compared to general anesthesia.

Area of Science:

  • Ophthalmology
  • Surgical Anesthesia

Background:

  • Open-angle glaucoma management often involves surgical intervention like trabeculectomy.
  • Local anesthesia is an alternative to general anesthesia for ophthalmic procedures.

Purpose of the Study:

  • To compare the outcomes of trabeculectomy performed under local anesthesia (lignocaine) versus general anesthesia.
  • To evaluate the effect of anesthesia type on bleb morphology and post-operative intraocular pressure (IOP).

Main Methods:

  • A comparative study involving 19 eyes undergoing primary trabeculectomy with subconjunctival lignocaine and 29 eyes under general anesthesia.
  • Assessment of bleb appearance (vascularity, wall thickness) and mean post-operative IOP.

Main Results:

Related Experiment Videos

  • A significantly higher incidence of avascular, thin-walled drainage blebs was observed in the local anesthesia group (77%) compared to the general anesthesia group (25%).
  • Mean post-operative IOP was significantly lower in eyes managed with local anesthesia.
  • Conclusions:

    • Subconjunctival lignocaine for trabeculectomy is associated with a higher rate of avascular blebs and improved IOP control.
    • The clinical significance and implications of thin-walled blebs warrant further discussion and evaluation.