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Updated: Jul 21, 2026

Biomimetic Materials to Characterize Bacteria-host Interactions
Published on: November 16, 2015
Bacterial adherence to hydrophilic polymer-coated polyurethane stents
B Jansen1, L P Goodman, D Ruiten
1Institute of Medical Microbiology and Hygiene, University of Cologne, Germany.
Abstract:
Biliary stent blockage by adherence of bacteria and formation of biofilm is a major problem in endoscopic stenting procedures. We have investigated bacterial adherence to hydrophilic polymer (Hydromer)-coated polyurethane stents in stationary and perfusion experiments. Adherence of gram negative and gram positive organisms under stationary conditions was similar between Hydromer-coated and non-coated control polyurethane stents; however, a marked 1 to 3 log reduction in adherence to Hydromer-coated stents occurred when perfusion experiments in phosphate buffer solution or bile were performed. The results suggest that Hydromer-coated polyurethane stents could be useful in preventing complications caused by biliary stent blockage.
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