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Updated: Aug 19, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Prolactinoma after craniocerebral trauma]
11. Universitäts-Frauenklinik, Wien.
A female patient, now twenty-four years old, suffered from a severe cerebral contusion in 1983 as a result of a car accident. At the time of the accident, she had a regular menstrual cycle. Since 1985, she has contracted oligomenorrhoea and since 1988 secondary amenorrhoea. In 1988, we diagnosed by CT-scan and NMR-imaging an excessive hyperprolactinaemia caused by a pituitary adenoma. Neither surgical intervention, nor conservative medication could reduce the prolactin level to normal. We suspect, that there is an association between the cranial injury and the appearance of the pituitary tumour.
A female patient, now twenty-four years old, suffered from a severe cerebral contusion in 1983 as a result of a car accident. At the time of the accident, she had a regular menstrual cycle. Since 1985, she has contracted oligomenorrhoea and since 1988 secondary amenorrhoea. In 1988, we diagnosed by CT-scan and NMR-imaging an excessive hyperprolactinaemia caused by a pituitary adenoma. Neither surgical intervention, nor conservative medication could reduce the prolactin level to normal. We suspect, that there is an association between the cranial injury and the appearance of the pituitary tumour.
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