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Distribution of bent DNA structures in the fission yeast centromere
1Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Japan.
Gene
|October 15, 1993
Abstract:
To gain a clue as to the functional significance of DNA curvature, we experimentally characterized the distribution of bent DNA structures throughout the 35-kb cen1 sequence, one of the isolated functional centromeric DNA of the fission yeast, Schizosaccharomyces pombe. It was revealed that a relatively large central portion of cen1, covering a 2.2-kb DNA sequence, displays a remarkable DNA curvature.