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Related Experiment Videos

[Fiber-enriched cereal for constipation and for hypercholesterolemia]

H S Odes1, H Lazovski, I Stern

  • 1Gastroenterology Dept., Soroka Medical Center, Beer Sheba.

Harefuah
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

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A high-fiber cereal effectively treated chronic constipation by increasing bowel movement frequency and stool softness. It also reduced serum cholesterol in hypercholesterolemia patients, though a larger dose or longer treatment may be needed for significant impact.

Area of Science:

  • Nutrition Science
  • Gastroenterology
  • Cardiovascular Health

Background:

  • Chronic constipation and hypercholesterolemia are common health issues.
  • Dietary fiber plays a crucial role in digestive and cardiovascular health.

Purpose of the Study:

  • To evaluate the efficacy of a mixed-grain, high-fiber cereal (Disivit) in treating chronic constipation and hypercholesterolemia.
  • To assess the impact of Disivit on bowel movement frequency, stool consistency, and serum cholesterol levels.

Main Methods:

  • Double-blind, cross-over trials were conducted on 20 constipated and 22 hypercholesterolemic patients.
  • Patients received 50 g/d of Disivit (12.5 g dietary fiber) or a low-fiber placebo for two-week periods.

Main Results:

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  • In constipated patients, Disivit significantly increased bowel movement frequency, softened stools, and reduced laxative intake.
  • Hypercholesterolemic patients showed a significant, albeit modest, 15% decrease in serum cholesterol levels.

Conclusions:

  • The high-fiber cereal (Disivit) is a promising dietary intervention for managing chronic constipation.
  • Further research with higher doses or longer treatment durations is recommended to ascertain Disivit's full potential for hypercholesterolemia management.