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[AIDS and opportunistic virus infections]
M Sugiura1, A Matsuura, S Imai
1Section of Virology of Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan.
[Hokkaido Igaku Zasshi] the Hokkaido Journal of Medical Science
|September 1, 1993
Abstract:
The opportunistic herpesvirus infections in AIDS are often life-threatening and the patients have lowered Epstein-Barr virus (EBV)-specific T cell cytotoxicity. On the other hand, the asymptomatic human immunodeficiency virus (HIV) carriers have potentially lowered EBV-specific cytotoxic T cell function, which is shown by exposure of the lymphocytes to an immunosuppressive substance. The EBV-specific T cell cytotoxicity may therefore tell the timing to cope with such opportunistic viral infections.