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Biliary tract infections treated with ciprofloxacin
G N Karachalios1, G Zografos, V Patrikakos
1Department of Medicine, Red Cross Hospital, Athens, Greece.
Infection
|July 1, 1993
Summary
Ciprofloxacin effectively treated severe biliary tract infections, including cholecystitis and cholangitis. This antibiotic regimen demonstrated a high cure rate with no major adverse effects in patients.
Area of Science:
- Infectious Diseases
- Pharmacology
- Gastroenterology
Background:
- Severe biliary tract infections, such as cholecystitis and cholangitis, pose significant clinical challenges.
- Effective antibiotic therapy is crucial for managing these serious infections and preventing complications.
Purpose of the Study:
- To evaluate the efficacy and safety of intravenous followed by oral ciprofloxacin for treating severe biliary tract infections.
- To determine the clinical and bacteriological cure rates associated with this treatment regimen.
Main Methods:
- A study involving thirty-two patients diagnosed with severe biliary tract infections (cholecystitis and cholangitis).
- Patients received intravenous ciprofloxacin, followed by oral ciprofloxacin for treatment.
- Clinical and bacteriological outcomes were assessed to determine treatment success and adverse events.
Main Results:
- Complete clinical and bacteriological cure was achieved in 28 out of 32 patients.
- Therapy failure was observed in four patients.
- No major adverse effects were reported during the study period.
Conclusions:
- Intravenous ciprofloxacin followed by oral administration is an effective treatment for severe biliary tract infections.
- The studied ciprofloxacin regimen is safe for patients with cholecystitis and cholangitis.
- This approach offers a promising therapeutic option for managing severe biliary infections.