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Streptokinase therapy in a five-year-old child with prosthetic mitral valve thrombosis

S S Kothari1, S H Wasir

  • 1Department of Cardiology, All India Institute of Medical Sciences, New Delhi.

Insights

Intravenous streptokinase therapy is a rare but safe and effective treatment for pediatric prosthetic valve thrombosis. This approach should be considered a primary therapy option for children, mirroring adult treatment protocols.

Area of Science:

  • Cardiology
  • Pediatric Medicine
  • Pharmacology

Background:

  • Prosthetic valve thrombosis (PVT) is a serious complication following cardiac valve replacement surgery.
  • PVT in pediatric patients is exceptionally rare, presenting unique clinical challenges.
  • Limited data exists on the efficacy and safety of thrombolytic therapy in children with PVT.

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