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Echovirus type 30 infection associated with aseptic meningitis in Nassau County, New York, USA
G P Leonardi1, A J Greenberg, P Costello
1Department of Pathology, Nassau County Medical Center, East Meadow, NY 11554.
Abstract:
An outbreak of echovirus type 30, primarily affecting infant under 1 year old, was documented in Nassau County, N.Y., USA. Twenty-four of the 40 infected patients were definitively diagnosed with aseptic meningitis. A positive correlation was found between the proportion of polymorphonuclear leukocytes and the overall cerebrospinal fluid white cell count.
Insights
An echovirus type 30 outbreak in New York primarily impacted infants under one year old, leading to aseptic meningitis in most cases. Cerebrospinal fluid analysis revealed a correlation between white cell count and polymorphonuclear leukocytes.
Area of Science:
- Virology
- Epidemiology
- Pediatrics
Background:
- Echovirus type 30 outbreaks can cause significant public health concerns, particularly in vulnerable populations.
- Infants are susceptible to severe complications from enteroviral infections.
Purpose of the Study:
- To document and characterize an outbreak of echovirus type 30 in Nassau County, NY.
- To identify the clinical manifestations and laboratory findings associated with the outbreak.
Main Methods:
- Retrospective analysis of clinical data from infected patients.
- Cerebrospinal fluid (CSF) analysis including cell counts and differential.
Main Results:
- Forty patients were infected with echovirus type 30, with a majority being infants under one year old.
- Twenty-four patients were diagnosed with aseptic meningitis.
- A positive correlation was observed between CSF white cell count and the proportion of polymorphonuclear leukocytes.
Conclusions:
- Echovirus type 30 poses a significant risk to infants, potentially causing aseptic meningitis.
- CSF analysis, specifically cell counts and differentials, can provide insights into the inflammatory response during echovirus infections.