[Refined diagnosis of C-reactive protein for the detection and course control of chronic inflammatory rheumatic...

When different methods of demonstration of C-reactive protein are used, results much deviating one from another may be observed. An exact diagnostics based on radial immunodiffusion with large range of recognition allows a quantitative registration of changes of C-reactive protein. The exact diagnostics of C-reactive protein seems to be of advantage especially with regard to comprehension and control of the course of subclinical processes. Together with the blood sedimentation rate the exact diagnostics of C-reactive protein gives the possibility of an improved objectivation of the process activity in chronic inflammatory rheumatic diseases.