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Immune regulation: learning from leprosy
1Division of Dermatology, University of California, Los Angeles, School of Medicine.
Hospital Practice (Office Ed.)
|November 15, 1993
Abstract:
The specific anergy seen in severe, disseminated leprosy appears to represent multifaceted actions of macrophages and suppressor T lymphocytes. Identification of cytokine mediation in these events helps to account for the immune system's "choice" of cellular versus humoral defenses--and points toward manipulation of cytokine switches for immunotherapy against infectious and autoimmune disease.