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Efficacy evaluations on five chlorhexidine teat dip formulations

P A Drechsler1, J K O'Neil, P A Murdough

  • 1Department of Animal and Food Sciences, University of Vermont, Burlington 05405.

Journal of Dairy Science
|September 1, 1993
PubMed
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New chlorhexidine digluconate teat dips show promise against Staphylococcus aureus but require further development for Streptococcus agalactiae infections in dairy cattle. Efficacy varied between experimental and natural exposure trials.

Area of Science:

  • Veterinary Medicine
  • Microbiology
  • Animal Health

Background:

  • Bovine mastitis remains a significant economic challenge in the dairy industry.
  • Effective postmilking teat disinfection is crucial for controlling intramammary infections (IMI).
  • Chlorhexidine digluconate is a common antimicrobial agent used in teat dips.

Purpose of the Study:

  • To evaluate the efficacy of developmental and commercial chlorhexidine digluconate teat dips against Staphylococcus aureus and Streptococcus agalactiae.
  • To assess the performance of these teat dips under both experimental and natural exposure conditions.

Main Methods:

  • Three developmental chlorhexidine digluconate teat dip formulations were tested in sequential experimental exposure trials.
  • Two commercial chlorhexidine digluconate teat dips were evaluated in natural exposure trials.

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  • Efficacy was determined by monitoring the incidence of new intramammary infections (IMI).

    • Main Results:

    • Developmental formulations were effective against Staphylococcus aureus but not Streptococcus agalactiae in experimental trials.
    • Conventional germicides did not effectively reduce new Streptococcus agalactiae IMI under experimental conditions.
    • In natural exposure trials, a 0.35% chlorhexidine dip showed 88.7% efficacy against Staphylococcus aureus and 51.4% against Streptococcus agalactiae. A 0.5% chlorhexidine product demonstrated 86% efficacy against Staphylococcus aureus and 56% against Streptococcus agalactiae.

    Conclusions:

    • Chlorhexidine digluconate teat dips show potential for controlling Staphylococcus aureus mastitis.
    • Further research is needed to improve efficacy against Streptococcus agalactiae.
    • Commercial chlorhexidine teat sanitizers demonstrated significant reductions in IMI caused by both pathogens in natural settings.