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Blockage of urethral catheters by bacterial biofilms
D J Stickler1, J B King, C Winters
1School of Pure and Applied Biology, University of Wales College of Cardiff, U.K.
Abstract:
We report the case of a 63-year-old woman whose indwelling urethral catheter became blocked regularly at 4-5 day intervals over a period of 10 weeks. 'Worm-like' structures 25-30 cm in length were found either in the catheter, completely occluding the lumen, or in the drainage tube thereby blocking the valve of the drainage bag. Electron microscopy showed that these structures were composed of bacteria, while culture revealed them to be mixed communities of Pseudomonas aeruginosa, Escherichia coli, Enterococcus faecalis and Proteus mirabilis. Following treatment with ciprofloxacin, catheter drainage continued freely for a further period of 10 weeks.
Insights
Recurrent catheter blockage in a woman was caused by bacterial biofilm. Ciprofloxacin treatment resolved the issue, ensuring continued catheter patency.
Area of Science:
- Urology
- Microbiology
- Infectious Diseases
Background:
- Indwelling urethral catheters are prone to encrustation and blockage.
- Bacterial biofilm formation is a common complication, leading to urinary tract infections and catheter failure.
Observation:
- A 63-year-old woman experienced recurrent catheter blockage every 4-5 days for 10 weeks.
- Large, 'worm-like' structures occluded the catheter lumen and drainage system.
Findings:
- Electron microscopy revealed the structures were bacterial biofilms.
- Cultures identified mixed bacterial communities: Pseudomonas aeruginosa, Escherichia coli, Enterococcus faecalis, and Proteus mirabilis.
Implications:
- This case highlights the significant impact of bacterial biofilm on indwelling catheter function.
- Effective antibiotic treatment, such as with ciprofloxacin, can restore catheter patency and prevent complications.