Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

First British standard for carcinoembryonic antigen (CEA)

D J Laurence, C Turberville, S G Anderson

    British Journal of Cancer
    |September 1, 1975
    PubMed
    Summary

    The National Institute for Biological Standards and Control established the first British Standard for carcinoembryonic antigen (CEA) in 1974. This standard ensures accurate quantitative assays for CEA levels.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The change in glycaemic control immediately after the 3rd COVID-19 vaccination in people with type 1 diabetes.

    Diabetic medicine : a journal of the British Diabetic Association·2023
    Same author

    The <sup>40</sup>Ar(d,p)<sup>41</sup>Ar cross section between 3-7 MeV.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2022
    Same author

    Foot ulceration and its association with mortality in diabetes mellitus: a meta-analysis.

    Diabetic medicine : a journal of the British Diabetic Association·2019
    Same author

    Developing a foot ulcer risk model: what is needed to do this in a real-world primary care setting?

    Diabetic medicine : a journal of the British Diabetic Association·2018
    Same author

    Success Rates in a Diabetes Specialist Nurse-Led Education Programme: Re-setting the Glucostat.

    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2017
    Same author

    Socioeconomic deprivation independently predicts painful diabetic neuropathy in type 2 diabetes.

    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2015

    Area of Science:

    • Biochemistry
    • Immunology
    • Clinical Chemistry

    Background:

    • Accurate measurement of biomarkers like carcinoembryonic antigen (CEA) is crucial for clinical diagnostics.
    • Standardization of biological assays is essential for reliable and reproducible results.

    Purpose of the Study:

    • To describe the establishment and characteristics of the first British Standard for carcinoembryonic antigen (CEA).
    • To provide a reference material for comparative quantitative assays of CEA.

    Main Methods:

    • Establishment of a freeze-dried powder standard for CEA.
    • Sealed in glass ampoules under pure dry nitrogen.
    • Each ampoule contains 100 units of CEA activity, designated 73/601.

    Main Results:

    • The National Institute for Biological Standards and Control (NIBSC) established the first British Standard for CEA in 1974.
    • The standard is prepared from material processed by the Chester Beatty Research Institute.
    • The standard is supplied as a freeze-dried powder in ampoules containing 100 units of CEA activity.

    Conclusions:

    • The 1974 British Standard for CEA provides a critical reference for quantitative assays.
    • This standardization facilitates inter-laboratory comparisons and enhances diagnostic accuracy.

    Related Experiment Videos