Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diabetic lipohypertrophy treated with suction-assisted lipectomy

F Samdal1, P F Amland, M Sandsmark

  • 1Department of Plastic Surgery, Norwegian National Hospital, Oslo.

Journal of Internal Medicine
|November 1, 1993
PubMed
Summary

Liposuction effectively treats insulin-induced lipohyperpertrophy in diabetic patients. This procedure, also known as "insulin tumors," showed excellent results with minimal side effects in a clinical study.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain.

International journal of obesity (2005)·2024
Same author

Higher frequency of hospitalization but lower relative mortality for pandemic influenza in people with type 2 diabetes.

Journal of internal medicine·2019
Same author

Diabetes prevalence among older people receiving care at home: associations with symptoms, health status and psychological well-being.

Diabetic medicine : a journal of the British Diabetic Association·2018
Same author

Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines.

Molecular metabolism·2017
Same author

Myostatin in relation to physical activity and dysglycaemia and its effect on energy metabolism in human skeletal muscle cells.

Acta physiologica (Oxford, England)·2015
Same author

The exercise-regulated myokine chitinase-3-like protein 1 stimulates human myocyte proliferation.

Acta physiologica (Oxford, England)·2015

Area of Science:

  • Endocrinology
  • Plastic Surgery
  • Dermatology

Background:

  • Insulin-induced lipohypertrophy is a common complication in diabetic patients requiring insulin therapy.
  • Accumulation of subcutaneous fat can cause cosmetic concerns and discomfort.

Purpose of the Study:

  • To evaluate the efficacy of liposuction for treating lipohypertrophy in insulin-dependent diabetic individuals.
  • To assess the safety and cosmetic outcomes of liposuction in this patient population.

Main Methods:

  • An open clinical study was conducted at the Norwegian National Hospital.
  • Five diabetic patients with insulin-induced lipohypertrophy underwent syringe-assisted liposuction under local anesthesia.
  • Outcomes were assessed using pre- and postoperative photographs and patient/surgeon evaluations on a four-point scale.

Related Experiment Videos

Main Results:

  • All patients achieved good to excellent cosmetic results following liposuction.
  • Minor surface irregularities were noted in two patients who had large fat volumes removed from the proximal anterior thighs.
  • No significant side effects or complications were reported during the study period.

Conclusions:

  • Liposuction is a successful treatment option for insulin-induced lipohypertrophy.
  • The procedure offers a safe and effective way to manage 'insulin tumors' with high patient satisfaction.