Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Position, guidance, and mapping in the developing visual system

C E Holt1, W A Harris

  • 1Department of Biology, University of California San Diego, La Jolla 92093-0322.

Journal of Neurobiology
|October 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cases Treated in the Louisville Marine Hospital.

Western journal of medicine and surgery·2024
Same author

Fractures of the Inferior Maxilla.

The American journal of dental science·2019
Same author

On Filling Carious Cavities between the Back Teeth.

The American journal of dental science·2019
Same author

A gene,imz, affecting the pH sensitivity of zygote formation inPhysarum polycephalum.

Current microbiology·2013
Same author

Specific inhibition by ethidium bromide of mitochondrial DNA synthesis in physarum polycephalum.

The Journal of cell biology·2009
Same author

Growth factors: a role in guiding axons?

Trends in cell biology·2007
Same journal

The molecular receptive range of an olfactory receptor in vivo (Drosophila melanogaster Or22a).

Journal of neurobiology·2006
Same journal

Consistent dynamics suggests tight regulation of biophysical parameters in a small network of bursting neurons.

Journal of neurobiology·2006
Same journal

Early condition, song learning, and the volume of song brain nuclei in the zebra finch (Taeniopygia guttata).

Journal of neurobiology·2006
Same journal

L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord.

Journal of neurobiology·2006
Same journal

Singing, but not seizure, induces synaptotagmin IV in zebra finch song circuit nuclei.

Journal of neurobiology·2006
Same journal

Developmental regulation of sensory axon regeneration in the absence of growth cones.

Journal of neurobiology·2006
See all related articles

Positional information guides retinal ganglion cell axons to form precise topographic maps in the brain. This review explores how these visual system gradients and navigational cues arise and function during development.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Visual System Research

Background:

  • Positional identity is crucial for accurate neural connections in the visual system.
  • Retinal projections to central targets rely on topographic mapping.

Purpose of the Study:

  • To review the origin and function of positional information and gradients in the retina.
  • To examine navigational cues used by retinal axons during development.
  • To analyze topographic cues in the tectum and their role in map formation.

Main Methods:

  • Literature review of studies on visual system development.
  • Analysis of research on retinal axon guidance and topographic mapping.
  • Examination of positional cues in the central nervous system and tectum.

Related Experiment Videos

Main Results:

  • Positional information and gradients arise in the retina and influence axon navigation.
  • Retinal axons utilize specific cues to orient and organize their projections.
  • Topographic maps are precisely formed in targets like the tectum, guided by local cues.

Conclusions:

  • Positional identity is fundamental for establishing retinotopic projections.
  • Developmental cues guide retinal axons to form functional topographic maps.
  • Neural activity may play a role in refining topographic precision.