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Delirium associated with Joseph disease

Y Fukutani¹, K Katsukawa, R Matsubara

¹Division of Neuropsychiatry, National Sanatorium Hokuriku Hospital, Toyama, Japan.

Journal of Neurology, Neurosurgery, and Psychiatry

|November 1, 1993

Summary

Joseph disease patients experienced sleep issues and delirium due to brainstem tegmental atrophy. Pathological findings confirmed degeneration in brainstem areas crucial for arousal and consciousness.

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Area of Science:

Neurology
Neuroscience
Pathology

Background:

Joseph disease is a rare, inherited neurodegenerative disorder.
Sleep disturbances and delirium are observed in advanced stages of the disease.