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Recurrent necrotizing enterocolitis

M D Stringer1, R J Brereton, D P Drake

  • 1Department of Paediatric Surgery, Hospitals for Sick Children, London, England.

Journal of Pediatric Surgery
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

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Sixteen infants experienced recurrent necrotizing enterocolitis (NEC) between 1981-1991. Most cases involved premature infants or those with congenital anomalies, with medical treatment proving successful in most instances.

Area of Science:

  • Neonatal Medicine
  • Pediatric Surgery

Background:

  • Recurrent necrotizing enterocolitis (NEC) presents a significant challenge in neonatal care.
  • Understanding risk factors and outcomes for recurrent NEC is crucial for improving patient management.

Purpose of the Study:

  • To analyze the incidence, characteristics, and outcomes of infants who developed recurrent NEC.
  • To identify potential associations between recurrent NEC and prematurity, congenital anomalies, or previous surgical interventions.

Main Methods:

  • Retrospective review of 16 infants diagnosed with recurrent NEC between 1981 and 1991.
  • Analysis of patient demographics, gestational age, birth weight, interval to recurrence, and treatment modalities.

Main Results:

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  • Recurrent NEC occurred in 16 infants, predominantly premature neonates or those with major congenital anomalies.
  • Medical treatment was successful in 11 patients; mortality was 12.5%, similar to primary NEC.
  • No consistent association was found with enteral feeding types, timing, or initial NEC management.

    • Conclusions:

    • Recurrent NEC is uncommon but carries a mortality rate comparable to initial NEC episodes.
    • Prematurity and congenital anomalies are key factors in recurrent NEC development.
    • Further research may elucidate specific underlying mechanisms for recurrent NEC.