Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Myasthenia gravis and scleroderma

R Bhalla1, W I Swedler, M B Lazarevic

  • 1Department of Medicine, University of Illinois at Chicago 60612.

The Journal of Rheumatology
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiolabeling of protected tryptophan with [<sup>18</sup>F]fluoromethyl tosylate: Formation of [<sup>18</sup>F]fluoromethyl ester of tryptophan instead of 1-N-[<sup>18</sup>F]fluoromethyl tryptophan methylester.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2019
Same author

Efficacy of alternate day Directly Observed Treatment Short-course (DOTS) in skeletal tuberculosis - A retrospective study.

The Indian journal of tuberculosis·2018
Same author

Challenges in the automated synthesis of [<sup>18</sup>F]-1-fluoroethyl tryptophan: Formation of both O- and N-alkylated products.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2017
Same author

Posterior Cruciate Ligament Tibial Avulsion treated with Open Reduction and Internal Fixation through the Burks and Schaffer Approach.

Malaysian orthopaedic journal·2017
Same author

Epidemiological features of skeletal tuberculosis at an urban district tuberculosis centre.

The Indian journal of tuberculosis·2016
Same author

Management of radioactive waste gases from PET radiopharmaceutical synthesis using cost effective capture systems integrated with a cyclotron safety system.

Journal of radiological protection : official journal of the Society for Radiological Protection·2016

Myasthenia gravis, an autoimmune condition, can coexist with other autoimmune diseases. This case study highlights a rare instance of scleroderma developing years after myasthenia gravis onset, suggesting a potential genetic link.

Area of Science:

  • Immunology
  • Rheumatology
  • Genetics

Background:

  • Myasthenia gravis is an autoimmune disorder characterized by antibodies targeting acetylcholine receptors.
  • It frequently co-occurs with other autoimmune conditions like thyroiditis, lupus, and rheumatoid arthritis.
  • Scleroderma is uncommonly associated with myasthenia gravis.

Observation:

  • This report details a patient who developed scleroderma six years after being diagnosed with myasthenia gravis.
  • This presentation is unusual given the typical associations of myasthenia gravis.

Findings:

  • The co-occurrence of myasthenia gravis and scleroderma is rare.
  • The human leukocyte antigen (HLA) B8/DR3 genotype may be implicated in the association between these two autoimmune diseases.

Related Experiment Videos

Implications:

  • Understanding the link between myasthenia gravis and scleroderma could improve diagnostic approaches.
  • Further research into shared genetic factors, like HLA-B8/DR3, may elucidate the pathogenesis of co-occurring autoimmune diseases.