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Updated: Aug 6, 2026

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
Published on: July 8, 2011
[Chemiluminescence of granulocytes in response to Pseudomonas strains isolated from various materials]
B Matynia1, A Szkarłat, E Pajdak
1Zakład Immunologii Klinicznej i Mikrobiologii, Akademii Medycznej im. M. Kopernika, Krakowie.
Abstract:
The study was aimed at comparison of chemiluminescence of granulocytes during their incubation with suspensions of Pseudomonas strains isolated from various sources. The study was performed on 136 strains isolated from clinical material. The results were correlated with resistance of these bacteria to bactericidal activity of serum and their ability to produce proteolytic enzymes. It was found that strains isolated from blood and pus weakly activate granulocytes in contrary to bacteria isolated from urine and feces. Ability to pronounced activation of granulocytes was without relation to susceptibility of a given strain to action of serum. But it correlated negatively with ability to production of proteolytic enzymes. These observations indicate existence of relation between characteristics of strain and type of clinical material from which it was isolated.

