Related Experiment Videos
[Giant coronary thrombus as a complication of Kawasaki disease]
K Kádár1, A Piskóthy, L Bendig
1Országos Kardiológiai Intézet, Budapest.
Insights
Kawasaki disease can cause serious coronary artery aneurysms. Anticoagulant therapy successfully dissolved a large thrombus in a giant coronary aneurysm, preventing complications in a pediatric patient.
Area of Science:
- Pediatric Cardiology
- Rheumatology
- Hematology
Background:
- Kawasaki disease is a leading cause of acquired heart disease in children.
- Coronary artery aneurysms are a significant complication, increasing the risk of thrombosis.
- Giant coronary aneurysms pose a critical management challenge.
Observation:
- A 3-year-old boy presented with giant coronary aneurysms following Kawasaki disease.
- Echocardiography revealed a large thrombus within the giant left coronary aneurysm.
- Coronary angiography confirmed the presence and extent of the aneurysms.
Findings:
- One week of anticoagulant therapy led to complete resolution of the coronary thrombus.
- The patient remained symptom-free during a 2-year follow-up period on anticoagulant therapy.
- This case represents the first documented instance of successful anticoagulant treatment for a massive thrombus in a giant coronary aneurysm due to Kawasaki disease in the country.
Implications:
- Anticoagulant therapy is a viable and effective treatment for coronary artery thrombosis in giant aneurysms secondary to Kawasaki disease.
- Early detection and management of thrombus formation are crucial for preventing adverse cardiovascular events.
- This successful outcome highlights the importance of tailored therapeutic strategies in pediatric cardiovascular complications.
Abstract:
We report the case of a 3 yrs old boy with the most serious complication of Kawasaki disease. 2 dimensional echocardiography detected multiple coronary aneurysms and in the giant left coronary aneurysm a thrombus formation. The thrombus disappeared after one week anticoagulant therapy. In addition the aneurysm were proved by coronarography. During the 2 years follow-up period the child is on anticoagulant therapy and he is symptom free. This is the first case in our country with a huge thrombus in a giant coronary aneurysm due to Kawasaki disease who was successfully treated using anticoagulant therapy.