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Related Experiment Videos

Delayed cold urticaria

O Bäck, A Larsen

    Acta Dermato-Venereologica
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Delayed cold urticaria, a rare condition, presents skin reactions 24-72 hours post-ice challenge. Some patients show low alpha1-antitrypsin and elevated C4 levels, suggesting further investigation.

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    Area of Science:

    • Immunology
    • Dermatology
    • Allergy

    Background:

    • Chronic urticaria diagnosis can be challenging.
    • Delayed hypersensitivity reactions are not fully understood.
    • Cold urticaria is a rare form of physical urticaria.

    Observation:

    • Describes five patients with delayed cold urticaria.
    • Urticarial skin response occurred 24-72 hours after ice challenge.
    • Two patients experienced clinically significant cold sensitivity.

    Findings:

    • Some patients exhibited low alpha1-antitrypsin levels.
    • Elevated C4 complement levels were observed in some patients.
    • Delayed urticarial response to cold stimulus.

    Implications:

    • Suggests cold provocation may aid in diagnosing chronic urticaria.
    • Highlights potential link between complement system and delayed cold urticaria.
    • Warrants further research into the pathophysiology of delayed cold urticaria.