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Retinoids in chemoprevention of head and neck carcinogenesis
S M Lippman1, S E Benner, W K Hong
1Department of Thoracic/Head and Neck Medical Oncology, University of Texas, M.D. Anderson Cancer Center, Houston 77030.
Preventive Medicine
|September 1, 1993
Abstract:
There is currently considerable excitement about the prospects of developing effective chemoprevention strategies for head and neck cancer. The field cancerization model provides the basic assumptions which guide current head and neck chemoprevention trials. The retinoid 13-cis-retinoic acid, as well as other agents, is currently being studied in clinical trials and will hopefully establish the role of chemoprevention in head and neck cancer.