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Efferent synapse mechanisms in chick hair cells
1Department of Physiology, Faculty of Medicine, University of Kyoto, Japan.
Progress in Brain Research
|January 1, 1993
Abstract:
Electrical stimulation of the efferent fiber to the hair cell is known to suppress peripheral auditory function. In isolated hair cells from the chick, acetylcholine (ACh) generated membrane hyperpolarization when a puff was applied at concentrations from 1 microM to 5 mM. Ionophoretic application of ACh generated a membrane hyperpolarization with a rapid time course. This is due to the increase of K conductance and is accompanied by the rise of the [Ca]i.