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Relationship between radiobiological hypoxia and direct estimates of tumour oxygenation in a mouse tumour model
M R Horsman1, A A Khalil, M Nordsmark
1Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus.
Abstract:
CDF1 mice were allowed to breathe either oxygen, carbogen or different concentrations of carbon monoxide gas. These treatments significantly altered the percentage of clonogenic hypoxic cells in a C3H mouse mammary carcinoma and these changes were found to correlate with direct measurements of tumour oxygenation obtained using an Eppendorf pO2 electrode.