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Published on: July 29, 2011
[Paroxysmal atrial fibrillation]
1Centre de rythmologie, hôpital Lariboisière, Paris.
Insights
Paroxysmal atrial fibrillation, a common arrhythmia, is hard to diagnose due to subtle symptoms. Early detection and management, including anticoagulants and antiarrhythmic drugs, are crucial for preventing embolism and improving outcomes.
Area of Science:
- Cardiology
- Electrophysiology
Context:
- Paroxysmal atrial fibrillation is the most common cardiac arrhythmia, increasing with age.
- Diagnosis is challenging due to often absent or misleading symptoms.
- Associated with various heart diseases and arterial hypertension.
Purpose:
- To discuss the diagnosis and management of paroxysmal atrial fibrillation.
- To highlight the risks of embolism and the role of anticoagulants and antiarrhythmic drugs.
Summary:
- Diagnosis relies on electrocardiogram, aided by Holter monitoring or patient-triggered recordings.
- Intracavitary electrophysiological study is used in specific cases.
- Atrial fibrillation increases the risk of peripheral and cerebral embolism (5% per annum).
Impact:
- Anticoagulant therapy effectively reduces embolism risk without requiring excessive treatment.
- Antiarrhythmic drugs help maintain sinus rhythm, indicated for symptomatic patients or those with significant cardiopathy.
- Atrial fibrillation signifies an unfavorable prognosis, increasing sudden death risk.
Abstract:
Paroxysmal atrial fibrillation is the most frequent of cardiac arrhythmias and its frequency increases with age. Its diagnosis is difficult since the symptoms are often absent or misleading. It is based on electrocardiogram performed during the attack, and this has been made easier by the Holter technique or by sequential recordings triggered by the patient himself. It is only in special cases, when percritical recordings could not be made that intracavitary electrophysiological study is used to obtain indirect arguments in favour of the diagnosis. All heart diseases can be attended by this cardiac rhythm disorder which usually marks an unfavourable turn in the course of the disease, with an increased risk of sudden death in the end. But in most cases the only disorder found is a common arterial hypertension. Atrial fibrillation carries a risk of peripheral, and in particular cerebral, embolism evaluated at 5% per annum. This risk is high in patients with cardiopathy, but it also exists even with a normal heart. The value of anticoagulants has been demonstrated by large controlled studies, but it is important to know that a very strong anticoagulant treatment is unnecessary to reduce the risk of embolism. Only antiarrhythmic agents can maintain the patients in sinus rhythm for as long as possible before the passage to permanent fibrillation. Although no beneficial effect on mortality has been proved, these drugs are indicated for patients who have very marked symptoms or a major cardiopathy.(ABSTRACT TRUNCATED AT 250 WORDS)
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