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[A treatment method for chronic parenchymatous parotitis]

P I Ivasenko, A Iu Lobastov, D A Potashov

    Stomatologiia
    |July 1, 1993
    PubMed
    Summary

    This study introduces a novel therapy for chronic parenchymatous parotitis using microdoses of short-acting insulin and calcium pantothenate. The treatment effectively restores parotin levels, offering a safe and easily administered option for patients.

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    Area of Science:

    • Endocrinology
    • Otorhinolaryngology
    • Pharmacology

    Background:

    • Chronic parenchymatous parotitis is characterized by reduced parotin production.
    • Parotin, an insulin-like substance, is crucial for parotid gland function.
    • Current therapeutic options for chronic parotitis are limited.

    Purpose of the Study:

    • To propose and evaluate a novel therapeutic method for chronic parenchymatous parotitis.
    • To investigate the efficacy of microdosed insulin and calcium pantothenate in treating parotitis.
    • To assess the safety and applicability of the proposed treatment.

    Main Methods:

    • A therapeutic regimen involving short-acting insulin in microdoses was developed.
    • A 5% calcium pantothenate solution was used to enhance insulin's local effect and receptor sensitivity.

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  • The method was applied to 42 patients diagnosed with chronic parenchymatous parotitis.

    • Main Results:

    • The treatment demonstrated effectiveness in managing chronic parenchymatous parotitis.
    • Patients were able to self-administer the therapy with ease.
    • The therapeutic approach exhibited minimal to no contraindications.

    Conclusions:

    • The suggested method offers an effective and accessible treatment for chronic parenchymatous parotitis.
    • The combination of microdosed insulin and calcium pantothenate shows promise for parotid gland dysfunction.
    • Further research may explore long-term outcomes and broader applications.