Related Experiment Video
Updated: Aug 19, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[Periodontal function and nonspecific resistance in the dynamics of experimental hypo- and hyperthyroidism]
Abstract:
Morphologic study of white rat periodontal tissue and assessment of nonspecific resistance of the body by whole blood antibacterial activity, skin bactericidal activity, blood serum and mixed salivary lysozyme activity were carried out over the course of experimental hypo- and hyperthyrosis starting from day 5 to day 90. The detected pathologic changes in the periodontium were in line with the time course of nonspecific resistance of the body. In hypothyrosis an earlier depression of nonspecific resistance factors was parallelled by earlier and more marked inflammatory destructive processes in the rat periodontium as compared to that in hyperthyrosis.
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