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[Damage caused by monoclonal immunoglobulins and possibilities of therapy. 2]
1II. interní klinika Fakultní nemocnice, Brno, Bohunice.
Vnitrni Lekarstvi
|October 1, 1993
Abstract:
Monoclonal immunoglobulins (M-Ig) cause due to their chemical structure and physical properties some pathological manifestations. In the text all skin changes are analyzed which are supposed to be associated with M-Ig. Some light chains form amyloid masses which can damage almost all organs. M-Ig can perhaps enhance also the capillary permeability although their role in the capillary leak syndrome remains obscure.