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Haematological and morphological changes in experimental anisakiasis in pigs
J Rokicki1, M Piskorzyńska, J Tokarski
1Department of Invertebrate Zoology, University of Gdańsk.
Wiadomosci Parazytologiczne
|January 1, 1993
Summary
This study investigated parasitic infection (anisakiasis) in pigs, finding similar blood changes in both stress-sensitive and stress-resistant animals. However, stress-sensitive pigs exhibited more severe stomach tissue reactions to the nematode larvae.
Area of Science:
- Veterinary Parasitology
- Animal Physiology
Background:
- Anisakiasis is a parasitic disease caused by nematode larvae.
- Halothane sensitivity in pigs is a model for stress response.
Purpose of the Study:
- To compare haematological and organic changes in halothane-sensitive and halothane-resistant pigs experimentally infected with Anisakis simplex.
- To investigate the impact of parasitic load on stress-related physiological responses.
Main Methods:
- Experimental infection of two groups of pigs (3 animals each) with A. simplex larvae.
- Administration of different larval doses to each group.
- Monitoring of haematological parameters (leucocytes, neutrophils, lymphocytes, monocytes, eosinophils).
- Histopathological examination of stomach tissues.
Main Results:
- Leucocyte counts, including neutrophils, lymphocytes, monocytes, and eosinophils, showed variations but were similar between halothane-sensitive and halothane-resistant pigs.
- Halothane-sensitive pigs displayed significantly greater reactive changes in the stomach submucosa compared to resistant pigs.
- Nematode larvae were identified within the submucosa of the stomach in halothane-sensitive pigs.
Conclusions:
- Haematological responses to experimental anisakiasis are comparable between halothane-sensitive and halothane-resistant pigs.
- Halothane sensitivity is associated with a more pronounced local inflammatory and reactive response in the stomach submucosa following nematode infection.