[Secretion of proteolytic enzymes following administration of nutrients into the duodenum and jejunum]

Infusion of nutrient fluids into the small intestine of dogs provoked the appearance of Pavlov's pouch juice displaying different proteolytic activity. The quantity of the juice was smaller with drop than with jet infusion. The total secretion of enzymes was more abundant in case of drip intraduodenal infusions of a milk and cream mixture, milk, aminocrovine as compared with its average level following introduction of 10 and 20 per cent solutions of sugar, lipomaize, emulsions prepared of dry dairy products and vegetable oil. The infusions into the duodenum and jejunum was followed by secretion of substantial amounts of the pancreatic juice displaying high activity of trypsin, close to that appearing in response to feeding on meat. The concentration of proteases in the intestinal chyme proved then sufficiently high.