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Are pill counts valid measures of compliance in clinical obstetric trials?
M B DuBard1, R L Goldenberg, R L Copper
1Department of Obstetrics and Gynecology, University of Alabama at Birmingham 35233-7333.
American Journal of Obstetrics and Gynecology
|November 1, 1993
Abstract:
We compared pill counts with a biochemical measure of compliance in 283 women who participated in a randomized double-blind trial that evaluated the efficacy of low-dose aspirin in the prevention of preeclampsia. Subjects whose pill counts indicated a usage > 100% were less compliant than women with lower pill counts.