Related Experiment Video
Updated: Aug 10, 2026
08:58
Procedures of Laboratory Fumigation for Pest Control with Nitric Oxide Gas
Published on: November 24, 2017
Nitrogen dioxide and respiratory illnesses in infants
J M Samet1, W E Lambert, B J Skipper
1Department of Medicine, University of New Mexico Medical Center, Albuquerque 87131.
The American Review of Respiratory Disease
|November 1, 1993
Summary
Residential exposure to nitrogen dioxide (NO2) did not increase respiratory illnesses in infants. This study found no significant link between NO2 levels in homes and the incidence or severity of infant respiratory conditions.
Area of Science:
- Environmental Health
- Pediatric Respiratory Medicine
- Epidemiology
Background:
- Nitrogen dioxide (NO2) is a common air pollutant from gas appliances.
- Indoor NO2 exposure is a potential risk factor for infant respiratory illnesses.
Purpose of the Study:
- To investigate the association between residential nitrogen dioxide (NO2) exposure and the incidence and severity of respiratory illnesses in infants during their first 18 months of life.
Main Methods:
- A prospective cohort study of 1,205 healthy infants from non-smoking homes.
- Mothers reported respiratory symptoms and illnesses bi-weekly.
- Indoor NO2 concentrations were measured using passive samplers in bedrooms.
Main Results:
- No consistent increase in illness incidence was observed with higher NO2 exposure or specific stove types.
- Multivariate analyses, adjusting for confounders, showed no significantly elevated odds ratios for NO2 exposure.
- Illness duration, an indicator of severity, was not associated with NO2 exposure levels.
Conclusions:
- Residential exposure to nitrogen dioxide (NO2) from gas stoves does not appear to increase the incidence or severity of respiratory illnesses in infants.
- Findings are applicable to homes with gas stoves in less polluted areas of the United States.
More Related Videos
05:46A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
08:23Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Related Concept Videos
01:05Breathing
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
01:202° Amines to N-Nitrosamines: Reaction with NaNO2
Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
01:23Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
01:17Pulmonary Cycle: Exhalation
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
01:29Microbiota of the Respiratory Tract
The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
01:29Respiratory Syncytial Virus Disease
Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...