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Handling punctate keratitis resulting from systemic cytarabine
S Friedland1, N Loya, A Shapiro
1Department of Ophthalmology, Beilinson Medical Center, Petah Tiqva, Israel.
Annals of Ophthalmology
|August 1, 1993
Abstract:
A young patient with acute myelogenous leukemia was treated with high-dose cytarabine (3.0 g/m2 every 12 hours). After five days of treatment, he developed severe photophobia and decreased visual acuity. On examination, progressive punctate keratitis was found. We discuss the mechanism of the cytarabine-induced corneal toxicity and the prophylactic use of topical corticosteroids.