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[Sertoli-Leydig tumors in children. 2 case reports]
R Mariani1, A Taleb-Figueroa, F Bastiani-Griffet
1Service de Pédiatrie, Hôpital de Cimiez, Nice.
Summary
Sertoli-Leydig tumors, rare ovarian growths, can cause virilization and adnexal torsion in young girls. Early diagnosis via imaging and hormone levels, followed by surgery, typically leads to a full recovery.
Area of Science:
- Gynecologic Oncology
- Pediatric Endocrinology
- Reproductive Medicine
Background:
- Sertoli-Leydig cell tumors (SLCTs) are rare ovarian neoplasms originating from the embryonic gonad's mesenchymal and sexual cord components.
- These tumors can present with significant clinical manifestations, particularly in pediatric and adolescent populations.
- SLCTs are known for their potential to produce androgens, leading to signs of virilization.