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Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens
J R Johnson1, T Berggren, A J Conway
1Department of Medicine, University of Minnesota, Minneapolis 55455.
Antimicrobial Agents and Chemotherapy
|September 1, 1993
Abstract:
Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by < or = 64 micrograms of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r2 = 0.93, P = 0.0001).