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Related Experiment Videos

Clinical cardiopulmonary bypass without systemic anticoagulation

R D Dowling1, M E Brown, R O Whittington

  • 1Department of Cardiothoracic Surgery and Anesthesiology, University of Pittsburgh, PA 15216.

The Annals of Thoracic Surgery
|November 1, 1993
PubMed
Summary

Heparin-coated perfusion systems enable cardiopulmonary bypass with reduced heparin. This case study shows a successful aortic valve replacement without systemic anticoagulation using such a system.

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Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Science
  • Hematology

Background:

  • Heparin-coated circuits reduce systemic heparinization during cardiopulmonary bypass.
  • Patients with contraindications to anticoagulation pose challenges for cardiac surgery.
  • End-stage liver disease and severe aortic stenosis necessitate complex surgical management.