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Catastrophic vasoconstriction after protamine reversal of heparin anticoagulation in the goat

R Tominaga1, W A Smith, H Harasaki

  • 1Department of Biomedical Engineering and Applied Therapeutics, Cleveland Clinic Foundation, Ohio.

Artificial Organs
|September 1, 1993
PubMed

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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...