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A case of fetal intestinal tract distensions: prenatal biochemical and ultrasound evaluation
T Stefos1, I Georgiou, M Syrrou
1Department of Obstetrics and Gynecology, University of Ioannina, Greece.
Insights
Elevated alkaline phosphatase isozyme and prealbumin in amniotic fluid can signal fetal intestinal issues. These markers aid in the early diagnosis of fetal intestinal distension and other abnormalities during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Biochemistry
Background:
- Fetal intestinal tract abnormalities are significant pregnancy complications.
- Ultrasound is used for identifying these abnormalities, especially fetal intestinal obstructions.
- Early diagnosis is crucial for managing these conditions.
Abstract:
Fetal intestinal tract abnormalities can be pregnancy complications at all maternal ages. There have been reports of ultrasound identification of these abnormalities, particularly of fetal intestinal obstructions. We report the first case to our knowledge of elevated levels of the intestinal isozyme, alkaline phosphatase, in the amniotic fluid and blood serum and also the presence of prealbumin in the amniotic fluid of a fetus with extensive intestinal distension and polyhydramnios. It was revealed that the alkaline phosphatase intestinal isozyme as well as protein electrophoresis for abnormal albumin bands in the amniotic fluid are valuable markers for the early diagnosis of the above-mentioned fetal abnormalities.