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Updated: Aug 15, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

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Tumor-rejection antigens recognized by T lymphocytes

O J Finn1

  • 1University of Pittsburgh School of Medicine, Pennsylvania 15261.

Current Opinion in Immunology
|October 1, 1993
PubMed

Generations of immunologists have been searching for evidence to confirm the tantalizing notion that tumor-rejection antigens exist. If found, the ultimate reward was the possibility that these molecules might be used to induce tumor-specific immunity and effect tumor rejection. Until recently rewards have been few and far between. That is changing. The immediate rewards have become more satisfying and the ultimate reward almost palpable.

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