Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Correcting for factors affecting ABR wave V latency

G R Lightfoot1

  • 1Department of Clinical Engineering, Royal Liverpool University Hospital.

British Journal of Audiology
|June 1, 1993
PubMed
Summary

Auditory brainstem response (ABR) wave V latency is influenced by age, sex, hearing loss, and stimulus intensity. Accounting for these factors, particularly sensation level and audiogram slope, is crucial for accurate retrocochlear dysfunction assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Audiometer calibration: interpreting and applying the standards.

British journal of audiology·2000
Same author

Bone conduction errors at high frequencies: implications for clinical and medico-legal practice.

The Journal of laryngology and otology·1993
Same author

ABR screening for acoustic neuromata: the role of rate-induced latency shift measurements.

British journal of audiology·1992
Same author

False positive retrocochlear ABR results.

British journal of audiology·1988
Same author

Commonly used terms in pure tone and audiometry.

British journal of audiology·1981
Same author

Air-borne radiation from bone conduction transducers.

British journal of audiology·1979

Area of Science:

  • Audiology
  • Neuroscience
  • Biomedical Engineering

Background:

  • Auditory brainstem response (ABR) wave V latency is a key metric for assessing auditory pathway function.
  • Previous research indicates subject and technical factors influence ABR latency, necessitating corrections for reliable retrocochlear dysfunction detection.

Purpose of the Study:

  • To investigate the impact of subject age, sex, hearing loss, and stimulus intensity on ABR wave V latency.
  • To determine the most effective way to incorporate these factors for latency analysis, excluding retrocochlear pathology.

Main Methods:

  • Regression analysis was performed on ABR wave V latency data from 189 clinical subjects.
  • Factors analyzed included subject age, sex, hearing loss, and stimulus intensity.
  • Sensation level and audiogram slope were derived to represent hearing loss and intensity effects.

Main Results:

  • All four investigated factors (age, sex, hearing loss, stimulus intensity) significantly affected ABR wave V latency.
  • A combined sensation level variable, incorporating hearing loss and stimulus intensity, along with audiogram slope, provided the most effective representation of latency influences.

Conclusions:

  • Subject age, sex, hearing loss, and stimulus intensity are significant determinants of ABR wave V latency.
  • Incorporating sensation level and audiogram slope in latency analysis improves the accuracy of ABR interpretation, particularly when ruling out retrocochlear pathology.

Related Experiment Videos