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Diffuse alveolar hemorrhage following autologous bone marrow infusion
S Corso1, S J Vukelja, D Wiener
1Department of Hematology-Oncology, Brooke Army Medical Center, San Antonio, TX 78234-6200.
Bone Marrow Transplantation
|September 1, 1993
Summary
Diffuse alveolar hemorrhage (DAH) is a serious complication of autologous bone marrow transplantation (BMT). This case suggests dimethyl sulfoxide (DMSO) may trigger DAH following BMT.
Area of Science:
- Hematology
- Pulmonology
- Transplantation Medicine
Background:
- Autologous bone marrow transplantation (BMT) is a treatment for hematologic malignancies.
- Diffuse alveolar hemorrhage (DAH) is a rare but life-threatening complication of BMT.
- The pathogenesis of DAH post-BMT is not fully understood.