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Translocation (Y;1)(q12;q21) in acute leukemia
1Kanematsu Research Laboratories, Royal Prince Alfred Hospital, Camperdown, Australia.
Cancer Genetics and Cytogenetics
|October 15, 1993
Abstract:
This report documents one patient with myelodysplasia evolving into acute leukemia who showed a t(Y;1) translocation confirmed by in situ hybridization. Most of the q arm of the Y chromosome was translocated to an additional q arm of chromosome 1, resulting in trisomy 1q. To our knowledge only four other cases with this t(Y;1) have been reported.