[Nucleolar organizer region-associated proteins and estrogen receptor of endometrial adenocarcinoma]

The nucleolar organizer region-associated proteins (AgNOR) staining technique and estrogen receptor (ER) detective technique were applied to endometrial adenocarcinoma in grade 1-4 and endometrial cystic hyperplasia. The results showed that there was no significant difference of AgNOR numbers between the grade I endometrial adenocarcinoma and endometrial cystic hyperplasia, while a significant difference of the number, size and localization of the nuclei was observed between endometrial adenocarcinoma and grade 2-4 endometrial adenocarcinoma (P < 0.001). The ER content in well differentiated endometrial adenocarcinoma was more than poor differentiated ones.