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Growth hormone in adolescence. Normal and abnormal

J F Cara1

  • 1Department of Pediatrics, University of Chicago Pritzker School of Medicine, Illinois.

Endocrinology and Metabolism Clinics of North America
|September 1, 1993
PubMed
Summary

The adolescent growth spurt is a key pubertal change, with growth rates unmatched since infancy. This review covers normal growth, controlling factors, and growth hormone issues during this period.

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Area of Science:

  • Pediatric Endocrinology
  • Human Physiology
  • Adolescent Medicine

Background:

  • The adolescent growth spurt is a significant physiological event during puberty.
  • Growth velocity during this period is the highest after infancy.
  • Understanding this phase is crucial for identifying developmental abnormalities.

Purpose of the Study:

  • To review the pathophysiology of normal adolescent growth.
  • To discuss factors influencing growth during adolescence.
  • To examine growth hormone deficiency syndromes that manifest in adolescence.

Main Methods:

  • Literature review of pathophysiology.
  • Analysis of hormonal and genetic factors controlling growth.
  • Clinical case review of growth hormone deficiency.

Main Results:

  • Normal adolescent growth is a complex process regulated by multiple factors.
  • Growth hormone and other hormones play critical roles.
  • Growth hormone deficiency can present during adolescence with specific clinical features.

Conclusions:

  • Adolescent growth spurt pathophysiology is well-defined.
  • Factors controlling growth are multifaceted.
  • Timely diagnosis of growth hormone deficiency is essential for appropriate management.

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