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Keratopathy following retinal detachment surgery
Archives of Ophthalmology (Chicago, Ill. : 1960)
|November 1, 1978
Summary
Retinal detachment surgery with silicone oil can cause keratopathy. Deposits of calcium phosphate, not silicone, were found in the cornea’s Bowman’s layer in affected patients.
Area of Science:
- Ophthalmology
- Corneal Science
- Materials Science
Background:
- Silicone oil is used in retinal detachment surgery.
- Keratopathy can be a complication following such procedures.
Observation:
- Three patients developed identical keratopathy post-retinal detachment surgery with silicone oil.
- Microscopic examination of corneal tissue was performed.
Findings:
- Granular deposits were identified in the Bowman's layer of the cornea.
- Histochemical and electron-probe analysis confirmed these deposits as calcium phosphate.
- No silicone was detected within the corneal tissue.
Implications:
- This suggests a non-silicone etiology for the observed keratopathy.
- Calcium phosphate deposition may be a critical factor in post-surgical corneal complications.
- Further research is needed to understand the mechanism of calcium phosphate accumulation.